Targets, targeted targets and molecular imaging: new potential treatments, new treatments and new ways of assessing treatments

New Molecular Targets and Treatments for Pediatric Brain Tumors

MicroRNAs in Neurocognitive Dysfunctions: New Molecular Targets for Pharmacological Treatments?

BACKGROUND Neurodegenerative and cognitive disorders are multifactorial diseases (i.e., involving neurodevelopmental, genetic, age or environmental factors) characterized by an abnormal development that affects neuronal function and integrity. Recently, an increasing number of studies revealed that the dysregulation of microRNAs (miRNAs) may be involved in the etiology of cognitive disorders as...

Evolving treatments of virus-associated HCC: new targets and drugs.

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide. The major etiologies and risk factors for HCC development are well defined and some of the multiple steps involved in hepatocarcinogenesis have been elucidated in recent years. The therapeutic options fall into five main categories: (1) surgical interventions, incl. liver transplantation, (2) percutaneous inter...

Brain tumor stem cells: new targets for clinical treatments?

The observation of similarities between the self-renewal mechanisms of stem cells and cancer cells has led to the new concept of the cancer stem cell. In cases of leukemia, multiple myeloma, and breast cancer, cells with a high selfrenewal potential have been identified. Furthermore, investigators have shown these cells' ability to drive the formation and growth of the tumor. Brain tumors have ...

new varicosis treatments and new keynots

lower extremity venous varicosis is a very prevalent disease. approximately 15 - 25 percent of the general population suffer from some degree of this disease. in recent years many new and innovative treatments have been developed for the disease and nowadays customary treatments ( saphenous strapping and phlebotomy) are nearly obsolete. these new treatments include laser ablation, radio frequen...